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REFLECTIONS
                                                                                                                   Hypertension
     Hypertension Global Newsletter #10 2026



     TREATMENT AND BIOMARKERS                                                                                      Hypertension


          4. Aldosterone synthase inhibitors for resistant or uncontrolled hypertension: A network meta-analysis of randomized
            clinical trials. Elbahloul MA, et al. J Hypertens. 2026 Apr 1;44(4):542-552.

          5. High blood pressure in childhood and premature cardiovascular disease mortality. Freedman AA, et al. JAMA. 2025
            Nov 4;334(17):1555-1557.
          6. Medication adherence in hypertension: A cluster randomized clinical trial. Blecker S, et al. JAMA Cardiol. 2025 Sep
            1;10(9):914-921.

          7. Integrative proteomic profiling of blood pressure and hypertension. Aggarwal M, et al. Hypertension. 2026
            Jun;83(6):e26407.


     BLOOD PRESSURE MANAGEMENT


          8. Impact of intensive versus standard blood pressure control on cardiovascular events in hypertensive patients: A
            meta-analysis of randomized controlled trials. Prizão VM, et al. J Hypertens. 2026 Jan 1;44(1):49-55.

          9. Frailty index offers greater discrimination than age for optimal blood pressure targets: A pooled analysis of two
            randomized trials. Lyu Y, et al. Hypertension. 2026 Jun;83(6):e26397.
         10. Uncontrolled hypertension in young adults: A real-world analysis of 89,130 adults in the United States. Islam S, et
             al. Hypertension. 2026 Mar;83(3):e26081.

         11. Benefit-harm trade-offs of intensive blood pressure control versus standard blood pressure control on
             cardiovascular and renal outcomes: An individual participant data analysis of randomised controlled trials. Guo X,
             et al. Lancet. 2025 Sep 6;406(10507):1009-1019.









































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