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REFLECTIONS
Hypertension Global Newsletter #10 2026
TABLE OF CONTENTS
KEY ARTICLES
GUIDELINES AND SCIENTIFIC STATEMENTS
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/
AGS/AMA/ASPC/NMA/PCNA/ SGIM guideline for the
prevention, detection, evaluation and management
of high blood pressure in adults: A report of the
American College of Cardiology/American Heart
Association joint committee on clinical practice
guidelines. Jones DW, et al. Hypertension. 2025
Oct;82(10):e212-e316.
Single-pill combination therapy for the management
of hypertension: A scientific statement from
the American Heart Association. King JB, et al.
Hypertension. 2026 Mar;83(3):e00258.
TREATMENT
New drug therapies for hypertension. Azizi M, et al.
Lancet. 2026 Mar 7;407(10532):1014-1028.
Quadruple vs triple therapy for resistant
hypertension: The QUADRO trial. Taddei S, et al. Eur
Heart J. 2026 Feb 11:ehag022. doi: 10.1093/eurheartj/ integration of machine learning and artificial intelligence into
ehag022. Online ahead of print.
Blood pressure-lowering efficacy of antihypertensive
drugs and their combinations: A systematic review
and meta-analysis of randomised, double-blind,
placebo-controlled trials. Wang N, et al. Lancet. 2025
Aug 30;406(10506):915-925.
MEASUREMENT
Cuffless devices for the measurement of blood
pressure: A scientific statement from the American
Heart Association. Cohen JB, et al. Hypertension. 2026
Mar;83(3):e00254.
ARTIFICIAL INTELLIGENCE
Performance of large language models in analyzing
common hypertension scenarios. Zand J, et al.
Hypertension. 2026 Jan;83(1):225-234.
Artificial intelligence in cardiovascular medicine:
Focus on hypertension. Varzideh F, et al. Hypertension.
2026 Jun;83(6):e26094.
Artificial intelligence in cardiovascular
pharmacotherapy: Applications and perspectives.
Costa F, et al. Eur Heart J. 2025 Oct 1;46(37):3616-3627.
ADDITIONAL ARTICLES OF INTEREST
CONFERENCE CORNER
Hypertension
Welcome back to the REFLECTIONS Hypertension
Global Newsletter series, which draws on the expertise of
international physicians to summarise the latest clinical and
real-world evidence in the field of hypertension and reflect
Hypertension
on the clinical impact of these new data on the management
of patients with hypertension. Since our last newsletter,
many new and interesting publications have appeared in the
active field of clinical research in hypertension. Therefore,
the Scientific Planning Committee was tasked with choosing
from an extensive list of articles from high-quality scientific
journals. To make this last selection, we privileged novel
findings rather than confirmation papers, and articles
with a direct application to antihypertensive treatment in
routine clinical practice. In this newsletter, we will focus
on 1) the latest evolution of clinical practice guidelines,
2) advancements in pharmacological management and
the strong push for single-pill combinations, and 3) the
clinical care. As with previous newsletters, we invite you to
interact with this newsletter through links to commentary
videos from authors of the publications, short video clinical
perspectives from our Scientific Planning Committee, and to
explore the articles in depth through the hyperlinks provided.
Prof. Laurent (Chair)
SCIENTIFIC PLANNING COMMITTEE
Prof. Stéphane Laurent Prof. Diego Araiza
(France) (Mexico)
Dr. Om Narayan Prof. Zainab Raissuni
(Australia) (Morocco)
Dr. Juan Camilo Dr. Michal Fikrle
Pedreros Guerra (Czech Republic)
(Colombia)